MLH1 甲基化单基因单区段标准品
CBPE0257-0263
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索取COA
产品描述
产品数据库
| Introduction | ||||||
| Description | DNA methylation is an epigenetic modification, a form of chemical modification of DNA, which refers to the carbon 5 of cytosine in the genomic CpG dinucleotide under the action of DNA methyltransferase. covalently bonded to a methyl group. It can change genetic expression without changing the DNA sequence. MLH1, mutL homolog 1, is a tumor suppressor that dimerizes with Pms2 to form a component of the DNA mismatch repair (MMR) system, and is associated with microsatellite instability (MSI) and genomic stability. |
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| Technical Data | ||||||
| Classification | Cat No. | Name | Unit Size | Methylation level | ||
| Chr3:37034735-37034852(hg19) | ||||||
| 质控品 | 阳性质控品 | CBPE0257 | MLH1 Methylation Positive control | 1ug | 98.59% | |
| 阴性质控品 | CBPE0258 | MLH1 Methylation Negative control (< Cut off) | 1ug | 0.00% | ||
| 参考品 | 强阳性参考品-1 | CBPE0259 | MLH1 Methylation Reference Standard with > 90% | 1ug | 98.59% | |
| 强阳性参考品-2 | CBPE0260 | MLH1 Methylation Reference Standard with 10% | 1ug | 10.10% | ||
| 弱阳性参考品 | CBPE0261 | MLH1 Methylation Reference Standard with 3% | 1ug | N/A | ||
| 检测限参考品 | CBPE0262 | MLH1 Methylation Reference Standard with 1% | 1ug | 0.98% | ||
| 阴性参考品 | CBPE0263 | MLH1 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
| 精密度参考品 | CBPE0261 | MLH1 Methylation Reference Standard with 3% | 1ug | N/A | ||
| CBPE0263 | MLH1 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |||
| 特异性参考品 | 定制化 | |||||
| 备注 | 1. 质控品也叫准确度标准品，用于定性判断； 2. 参考品用于定性和定量的判断，其中强阳、弱阳、检测限、精密度、特异性的判定需要视具体项目而定，本产品的判定仅为内部标准； 3. 质控品用于性能评价，出厂检，试剂盒日常检测判定，参考品用于性能评价，出厂检； 4.上述产品只展示了部分结果，甲基化程度可以定制。 |
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| Product Information | ||||||
| Intended Use | Research Use Only | |||||
| Concentration | Download for COA | |||||
| Purity | Download for COA | |||||
| DNA electrophoresis | Download for COA | |||||
| Storage | 2-8°C | |||||
| Expiry | 36 months from the date of manufacture | |||||
| Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. | |||||
